![Cancer can spread to almost any part of the body, although different cancers are likely to metastasize to certain areas than others.](https://images.medicinenet.com/images/article/main_image/lung-cancer.jpg?output-quality=75)
Cancer can spread to almost any part of the body, although different cancers are likely to metastasize to certain areas than others. The most common site of metastasis for different primary cancer is tabulated below:
Cancer Type
Main Sites of Metastasis
Bladder
Bone, liver, lung
Breast
Bone, brain, liver, lung
Colon
Liver, lung, peritoneum
Kidney
Adrenal gland, bone, brain, liver, lung
Lung
Adrenal gland, bone, brain, liver, another lung
Bone, brain, liver, lung, skin, muscle
Ovary
Liver, lung, peritoneum
Pancreas
Liver, lung, peritoneum
Prostate
Adrenal gland, bone, liver, lung
Rectal
Liver, lung, peritoneum
Stomach
Liver, lung, peritoneum
Thyroid
Bone, liver, lung
Uterus
Bone, liver, lung, peritoneum, vagina
What is metastatic cancer?
Cancer that spreads from a primary site to a distant part of the body is known as metastatic cancer. For many types of cancer, it is also called stage IV cancer. When seen under the microscope, metastatic cancer cells have features similar to that of the primary cancer cells and not like the cells where the metastatic cancer is spread.
What is metastasis?
The process of cancer spreading to other parts of the body is called metastasis. Metastasis causes about 90% of death in people with cancer.
Metastasis can occur in three ways:
- The cancer cells invade the tissue surrounding the primary tumor.
- Cells can travel via the bloodstream to a distant part of the body.
- Cells can travel via lymph system to adjacent or distant lymph nodes.
What are the symptoms of metastatic cancer?
Some people will have no or minimal symptoms of metastatic cancer. The symptoms depend on the location of metastasis. Tumor metastasized to brain exhibits the following symptoms:
- Headache
- Dizziness
- Visual problems
- Speech problems
- Nausea
- Difficulty walking
- Confusion
- Personality changes
- Seizures
Symptoms of bone metastasis include:
- Fractures or breaking of bone with or without minor injury
- Severe back pain
- Leg numbness
- Difficulty with bowel or bladder control
- Pain
- Symptoms of lung metastasis include:
- Productive or nonproductive cough
- Coughing up blood
- Chest pain
- Shortness of breath
Symptoms of liver metastasis include:
- Pain
- Weight loss
- Nausea
- Loss of appetite
- Ascites (abdominal fluid)
- Jaundice (yellowing of the skin and the whites of the eyes, dark urine, and light-colored stool)
Symptoms of gastrointestinal tract metastasis include:
- Nausea
- Vomiting
- Early satiety
- Abdominal discomfort
- Weight loss
- Change in bowel habits
![](https://images.medicinenet.com/images/quiz/human-body/human-body-s1.jpg)
QUESTION
What percentage of the human body is water? See AnswerHow is metastatic cancer treated?
Metastatic cancer is primarily treated based on the original site of cancer. For example, if a person has lung cancer and cancer spreads to the liver, it is still treated with the same drugs used for lung cancer. In terminal conditions, making a person comfortable and easing the severity of pain (palliation) may be an option.
Brain metastasis
The treatment options include:
- Surgery
- Radiation therapy
- Gamma knife surgery
- Chemotherapy
- Steroids
Bone metastasis
The treatment options include:
- Drug therapy for bone metastasis that is not causing bone pain or danger of breaking
- Radiation therapy for fragile bone
Lung metastasis
The treatment options include:
- Thoracentesis (a procedure to remove the fluid to make breathing easier)
- Drug therapy
Liver metastasis
The treatment options include:
- Radiofrequency ablation
- Surgery
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Doctors, pharmacists, and other health-care professionals use abbreviations, acronyms, and other terminology for instructions and information in regard to a patient's health condition, prescription drugs they are to take, or medical procedures that have been ordered. There is no approved this list of common medical abbreviations, acronyms, and terminology used by doctors and other health- care professionals. You can use this list of medical abbreviations and acronyms written by our doctors the next time you can't understand what is on your prescription package, blood test results, or medical procedure orders. Examples include:
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- cap: Capsule.
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- JT: Joint
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- p.o.: By mouth. From the Latin terminology per os.
- q.i.d.: Four times daily. As in taking a medicine four times daily.
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- T: Temperature. Temperature is recorded as part of the physical examination. It is one of the "vital signs."
Targeted Therapy: What Are Invasion and Metastasis in cancer?
There are several proteins and cellular signals that cancerous or malignant tumor cells employ for promoting invasion and metastasis. Targeted cancer therapies are in development to chemically hinder invasion and metastasis. Targeted therapy, in general, by identifying and targeting cancer-causing factors. Targeted therapy medications do not directly kill the cancer cells, but work on the cellular level to stop their growth and prevent cancer from spreading to other parts of the body.