Stevia vs. Splenda: What’s the Difference?

Medically Reviewed on 8/31/2022
Stevia vs. Splenda: What's the Difference
Learn about the differences between stevia and Splenda and whether one is healthier than the other

Stevia and Splenda are both popular sweeteners used as sugar alternatives, offering sweetness without the added calories or spikes in blood sugar.

Learn about the differences between stevia and Splenda and whether one is healthier than the other.

What is stevia vs. Splenda?

Stevia

Stevia is a natural sugar alternative made from the leaves of the Stevia rebaudiana plant. The active chemical compounds in stevia are steviol glycosides, which are mainly made up of stevioside and rebaudioside. It is about 200 times sweeter than sugar.

Stevia cannot be broken down by the body, and therefore does not contribute to your calorie count. Stevia also has no glycemic index and does not cause blood sugar spikes since your body does not need insulin to metabolize it.

Splenda

Splenda is a low-calorie artificial sweetener made from sucralose. Sucralose is a type of indigestible artificial sugar. It is made via a chemical process that makes it 450-650 times sweeter than sugar.

It is essentially made calorie-free by replacing some sugar molecules called hydroxyl with chlorine.

What are the differences between stevia and Splenda?

Table. Stevia vs. Splenda characteristics
Stevia Splenda
Chemical components Made from Stevia rebaudiana plant, stevioside, and rebaudioside along with other compounds such as ascorbic acid, beta-carotene, calcium, iron, magnesium, phosphorus, potassium, protein, and zinc Made from sucralose
Level of sweetness 200 times sweeter than sugar 450-650 times sweeter than sugar
Forms available Powdered, liquid, granulated, dried Powdered, liquid, granulated, dried
Optimal use Beverages, desserts, sauces, and baked products Beverages
Causes blood sugar spikes No No
Natural or processed Natural Processed
Aftertaste Slightly bitter or licorice-like No aftertaste
Calorie content No calories Contains some calories
One serving size
  • Liquid: 5 drops or 0.2 mL
  • Powder: 1 teaspoon or 0.5 grams
  • Liquid: 1/16 teaspoon or 0.25 mL
  • Powder: 1 gram or 1 mL
Nutrients per serving (1 teaspoon or 0.5 grams)  Negligible amount of carbs, fat, protein, vitamins, and minerals 0.5 grams of carbs and 0.02 mg of potassium

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Which one should you choose?

Both stevia and Splenda are overall safe and calorie-free sugar substitutes, but research on their long-term health effects is still ongoing.

In general, purified stevia appears to be associated with the fewest health concerns. Sucralose has been shown to potentially increase the risk of inflammation and create potential carcinogens called chloropropanols when used for cooking or baking.

The American Heart Association (AHA) recommends limiting added sugars to no more than 100 calories a day for women (6 teaspoons a day) and no more than 150 calories for men (9 teaspoons a day). When choosing between stevia vs. Splenda, keep in mind their best uses and enjoy it in moderation.

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Medically Reviewed on 8/31/2022
References
Image Source: iStock image

The 5 Best (and worst) Sweeteners You Can Eat. https://health.clevelandclinic.org/5-best-and-worst-sweeteners-your-dietitians-picks/

The Truth About Stevia—The So-called “Healthy” Alternative Sweetener. https://www.acefitness.org/certifiednewsarticle/1644/the-truth-about-stevia-the-so-called-healthy-alternative-sweetener/

What to Know About Sucralose. https://www.webmd.com/diet/what-to-know-about-sucralose

Is Sucralose (Splenda) Bad for You? https://health.clevelandclinic.org/is-sucralose-splenda-bad-for-you/